Studying the Effect of Furosemide Injection on Pulmonary Artery Parameters in Dogs

Background and aim: Doppler ultrasonography is a suitable non-invasive method for examining vascular hemodynamics that using the Doppler effect and changing the frequency of the recoil of moving targets, the speed and direction of blood flow can be examined. The aim of this study is to evaluate the effect of Furosemide on pulmonary artery by determining vascular parameters in healthy and adult dogs. Materials and methods: Measurements were made by Doppler ultrasonography. In this study, ۵ dogs of native breed were studied. The injection was given intramuscularly at a dose of ۰.۲ mg per kilogram body weight. Vascular parameters of the pulmonary artery were measured before the injection of Furosemide and at ۱۵ and ۳۰ minutes after drug injection. These parameters include peak systolic velocity (PSV), resistive index (RI) and Pulsatility index (PI).   Results: The results showed that the changes occurred ۱۵ minutes after the injection. Thus, blood flow velocity changes from ۲۹ to ۳۰.۵, arterial resistance index from ۱.۵۶ to ۱.۴۴ and arterial heart rate index from ۵۲.۴ to ۲۱.۴. Conclusion: The results of the present study also show that the injection of Furosemide significantly increases blood flow velocity in the pulmonary artery.

کلیدواژه ها:

Doppler ultrasonography ، Furosemide ، Pulmonary Artery ، Dog ، اولتراسونوگرافی داپلر ، فروزماید ، شریان ریوی ، سگ