Seroloprevalence of Hepatits G Virus (HGV) in beta-Thalassemia Patients Jahrom-Iran, ۱۳۹۹

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 128

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شناسه ملی سند علمی:

MEDISM23_526

تاریخ نمایه سازی: 16 مهر 1401

چکیده مقاله:

Background and Aim : People who have multiple transfusions, such as Beta-thalassemia patients,are at risk for the hepatitis G virus (HGV) infection. The aim of the study was the determinationof serological prevalence of HGV and its associated factors in beta-thalassemia major patients inJahrom-Iran.Methods : This cross-sectional study, was done on ۹۱ beta-thalassemia patients referring to thethalassemia center, Jahrom-Iran, ۲۰۲۱. Blood samples were collected from the patients and anti-HGV antibodies were evaluated by ELISA methods. Serum levels of ALT, AST, ALP anddemographic data were extracted from patients' medical records. Descriptive analysis, X۲, and Ttestwere used for statistical analyses by SPSS-۱۶.Results : The prevalence anti-HGV IgG and IgM were ۱۷% and ۵%, respectively. There weresignificant relationships between the frequencies of anti-HGV antibodies and serum level of ALT,ASL, ALP and also with the history time of transfusion (P<۰.۰۵). But, there were no significantrelationships between the frequencies of anti-HGV antibodies with patients' sex and the mean ofage (P>۰.۰۵).Conclusion : HGV is one of the etiologic factors of hepatitis in thalassemia patients in Jahrom.Further comprehensive and molecular-based studies are recommended to explore the prevalenceof HGV and its role in hepatitis thalassemia patients

کلیدواژه ها:

Seroprevalence ، Hepatitis G virus (HGV) ، Sero-prevalence ، thalassemia ، Iran

نویسندگان

Abdolreza Sotoodeh Jahromi

Zoonoses Research center, Jahrom University of Medical Sciences, Jahrom, Iran

Fatemeh Sotoodeh Jahromi

Zoonoses Research center, Jahrom University of Medical Sciences, Jahrom, Iran

Masihollah shakeri

Zoonoses Research center, Jahrom University of Medical Sciences, Jahrom, Iran