The novel therapeutic strategy for obesity through the gutbrainaxis

Background and Aim : The interaction between commensal bacteria and the host is essential forhealth and the gut-brain axis plays a vital role in this regard. Obesity not only does disorder affectsthe health of the individuals, but also the economic and social aspects of communities are affectedby it. The presence of any dysbiosis in the composition of the gut microbiota disrupts in the gutbrainaxis, which in turn leads to an increase in appetite and then obesity. Because commontreatments for obesity have several drawbacks, the use of microbiota-based therapy in addition totreatment and prevention of obesity can have other numerous benefits for the individual. In thisreview, we intend to investigate the relationship between obesity and the gut-brain axis as well asnovel treatment strategies based on this axis with an emphasis on gut microbiota.Methods : -Results : -Conclusion : -

کلیدواژه ها:

gut–brain axis ، obesity ، dysbiosis ، gut microbiota ، probiotics ، prebiotics ، FMT