Blue light irradiation inhibits bacterial growth

Background and Aim : In addition to antibiotic therapy, there have been various types oftherapeutic methods developed to deal with bacterial infections. Nowadays, irradiation has beenintroduced as one of the therapeutic strategies in the treatment of various diseases and has attracteda lot of attention in research. Due to the growth of infectious diseases, it is necessary to provide avaluable and non-invasive treatment method that can overcome the limitations of other methodsand be a suitable alternative to them. In this regard, the use of irradiation to destroy bacteria hasbeen suggested, which can achieve this goal by producing free radicals and changing the bacterialcell structure. The purpose of this study is to investigate the effect of blue light irradiation on thegrowth of Gram-positive and Gram-negative bacteria.Methods : Staphylococcus aureus and Escherichia coli bacteria were spread on solid mediumplates. The plates were exposed to light-emitting diodes with wavelengths of ۴۳۵ nm with anenergy dose of ۳۷ J/cm۲Results : The results showed that irradiation had a significant effect in reducing the growth andnumber of colonies in both strains compared to the plates without the presence of irradiation.Conclusion : According to the conducted study, it is possible to suggest the irradiation method toinhibit bacterial growth, and this solution can help in the treatment of infectious diseases alongwith other treatment methods.

کلیدواژه ها:

Irradiation ، Gram-positive bacteria ، Gram-negative bacteria