Prevalence and antibiotic susceptibility pattern ofEnterobacter isolates in burn patients: A cross-sectional study in Northof Iran

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 120

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شناسه ملی سند علمی:

MEDISM23_217

تاریخ نمایه سازی: 16 مهر 1401

چکیده مقاله:

Background and Aim : The bacterial infections that prevail in the burnt patients continue to be acritical complication in the burnt patients and vary with time and place. Identification of bacterialpathogens with information on their antimicrobial susceptibility to burn wounds can help cliniciansto select appropriate medication procedures by providing them with suitable antibiotics forempirical treatment.Methods : In a ۳-year descriptive cross-sectional study, data were collected from all patients withburn wound infection caused by Enterobacter isolates referred to the Burn Injury Hospital innorthern Iran. Demographic and clinical information included age, sex, percentage of burns, ward,length of hospital stays, type of infection, outcome, and antibiotic susceptibility profile. Resultswere analyzed using SPSS software version ۲۴.Results : A total of ۱۵ cases (۲.۸%) of Enterobacter isolates were recovered from ۵۳۶ cases ofburn wound infection. ۹ cases of Enterobacter isolates (۶۰%) were related to male patients and ۶cases (۴۰%) were related to female patients. The mean age of patients was ۴۳.۵۳ ۱۹ ۱۹.۵ years.Also, ۹ cases of Enterobacter isolates (۶۰%) were isolated from ICU and ۶ cases (۴۰%) wereisolated from the burn surgery ward. The mean hospital stay was ۱۴.۹۷ ± ۱۴ days and the meanhospital stay until the infection was ۳.۶ ± ۳ days. Nine cases of enterobacterial isolates (۶۰%) werereported in patients with improvement and ۶ cases (۴۰%) were reported in patients who died. Thehighest frequency in the type of infection is related to skin infections with a frequency of ۹ (۶۰%).The highest antibiotic resistance was related to ciprofloxacin (۸۱.۸%), followed by meropenem(۸۰%) and gentamicin (۷۵%). The most effective antibiotic was amikacin with ۷۰% efficacy.Conclusion : Enterobacter species isolation was low in the burn center we studied. However, thesignificant drug resistance of organisms makes them clinically important pathogens. Also, theresults of a recent study on the emergence of antibiotic susceptibility to infection with Enterobacterisolates can be a serious warning to increase the cost of treatment and hospitalization, as well asreduce the quality of patients' health. Preventing it requires targeted optimization of treatmentprotocols based on laboratory results or based on an antibiotic susceptibility pattern to reduceunwanted allergies.

نویسندگان

Mohammadreza Mobayen

Burn and regenerative medicine research center, Guilan University of medical sciences, Rasht, Iran

Mahsa Sadeghi

Burn and regenerative medicine research center, Guilan University of medical sciences, Rasht, Iran

Hadi Sedigh Ebrahim-Saraie

Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran

Meysam Hasannejad-bibalan

Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

Tofigh Yaghoubi

Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran

Mahdieh Teymouri

Burn and regenerative medicine research center, Guilan University of medical sciences, Rasht, Iran