Prevalence and pattern of antibiotic resistance of bacterialagents isolated from culture in patients with urinary tract infectionsreferred to Khorramabad teaching hospitals in ۲۰۲۱

Background and Aim : Urinary tract infection is one of the most common infectious diseases andincreasing resistance of bacteria to antimicrobial agents is a major problem in the treatment ofurinary tract infections worldwide. Patients diagnosed with urinary tract infection referred toKhorramabad teaching hospitals were designed and performed in ۲۰۲۱.Methods : Sampling was performed using the standard mid stream method. Information aboutantibiotic resistance and susceptibility as well as the type of pathogen were collected and recordedby the laboratory of Khorramabad Teaching Hospitals through the report of urine culture results.After collection, the data were entered into Stata version ۱۶ statistical software and analyzed usingstatistical methods.Results : In this study, the highest frequency of reported pathogens was related toEscherichiacoli(۴۱.۲۰% -۱۰۳ patients) followed by Staphylococcus saprophyticus(۲۰.۸۰% -۵۲) and Klebsiellapneumoniae(۱۸.۴۰% -۴۶) , respectively. Also, the highest antibiotic resistance was reportedagainst amoxicillin(۵۹.۲%) and then ampicillin(۵۳.۶%) and the lowest antibiotic resistance againstimipenem(۱۱.۶%) and then amikacin(۱۷.۶%).In this study, between antibiotic resistance. Therewas a statistically significant relationship between biotics compared to amoxicillin, ampicillin andimipenem with the previous history of antibiotic use.(P <۰.۰۵).Conclusion : It seems that amikacin and imipenem antibiotics are suitable drugs to startexperimental treatment until the antibiogram response is ready in patients with a diagnosis ofurinary tract infection.

کلیدواژه ها:

Urinary tract infection ، antibiotic resistance ، bacterial agents