The effect of Elaeagnus Angustifolia L extract oncancer cells
محل انتشار: پانزدهمین کنگره بین المللی سرطان پستان
سال انتشار: 1400
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 275
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شناسه ملی سند علمی:
ICBCMED15_012
تاریخ نمایه سازی: 28 شهریور 1401
چکیده مقاله:
Breast cancer (BC) usually affects womenworldwide and accounts for ۲۵% of allcancers. Many factors can cause thisdisease, the most important of which areenvironmental and genetic related to theonset of breast cancer. Breast cancer inwomen is classified into five molecularsubgroups. Elaeagnus Angustifolia (EA)extract is rich in flavonoids. EA has severaltherapeutic and medicinal properties,including anti-mutagenic, antioxidanteffects. EA extract can reduce theprogression of human cancer by inhibitingangiogenesis and cell invasion through theErk۱ / Erk۲ signaling pathways. EA hasanti-cancer effects due to the essentialflavonoids. flavonoids increase p۵۳expression and stop the cell cycle in the G۲/ M phase.This study investigates the effect of EAextract on cancer cells. SID,MEDLINE, PubMed, and Scopusdatabases from ۲۰۱۰ to ۲۰۲۱ wereused for this research.
کلیدواژه ها:
نویسندگان
ali rajabi
Department of Tissue Engineering and Applied Cell Science, Shiraz University of Medical Science, Shiraz, Iran
Hengameh Dortaj
Department of Tissue Engineering and Applied Cell Science, Shiraz University of Medical Science, Shiraz, Iran
Sareh ortaj
Department of Pharmacy, Dubai Medical University, Dubai, UAE
Majid Pourentezari
Department of Anatomy and Cell Biology, Shahid Sadoughi University of Medical Science, Yazd, Iran
Mohammad Rajabi
Department of Orthotics and Prosthetics, Isfahan University of Medical Scinces, Isfahan, Iran