ACUTE MYOCARDIAL INFARCTION IN ISFAHAN, IRAN: HOSPITALIZATION AND ۲۸TH DAY CASE-FATALITY RATE

Abstract    BACKGROUND: This study aimed to investigate ۲۸-day case fatality rate due to acute myocardial infarction (MI) in Isfahan using a standardized surveillance system.    METHODS: A prospective longitudinal study was performed on hospitalized myocardial infarction patients in Isfahan, Iran from ۲۰۰۰ to ۲۰۰۴. All hospitalizations due to myocardial infarction (MI) events were recorded via a system adopted from “World Health Organization Monitoring Trends and Determinants in Cardiovascular Disease” (MONICA) project, with ignoring MONICA age limitation. Patients were followed and their families enquired about their patients survival status at ۲۸th day with phone calls and if not available at home visits.    RESULTS: Age-adjusted hospital admission rate showed an increase during the study period, rising from ۱۳۱.۶۷ to ۲۰۹.۲۷ per ۱۰۰۰۰۰, but slowed toward the end of the study. Patients’ mean age was ۶۲.۳۵±۱۲.۶۴, with one third of events documented among female patients. Young patients (< ۴۵ years old) comprised ۸.۶% of hospitalizations which remained nearly constant through the study. The corresponding figure was about ۲۸% for patients aged less than ۵۵ years. The ۲۸-day case fatality rate was ۲۳.۱% for women and ۱۳.۲% for men. For individuals aged ۳۵-۶۴ years, the fatality rate was ۱۳.۰% for women and ۷.۷% for men.     CONCLUSION: This study showed an increase in myocardial infarction hospital admission rate in Isfahan but the rate of increase is decreasing. A multi-centric community-based myocardial infarction incidence study is needed to elucidate myocardial infarction epidemiology in Iran.      Keywords: Myocardial Infarction (MI), Epidemiology, Prevention and control, Cardiovascular diseases, Iran, Fatality rate.