One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study

BACKGROUND: Cardiovascular diseases (CVDs) are one of the main concerns of health care systems. The aim of this study was to investigate the most important prognostic factors of heart failure (HF) and their survival outcomes in patients in Birjand, East of Iran.METHODS: A total of ۱۹۴ systolic HF patients hospitalized in Birjand Valiasr hospital were followed up for ۱۲ months in ۲۰۱۶, and those with reduced left ventricle ejection fraction (LVEF < ۵۰%) were included in this study. Kaplan-Meier and Cox proportional hazard analysis were used to determine the association of each factor with events.RESULTS: The mean age of patients was ۶۸.۲۳ ± ۱۳.۴۰ (۲۷-۹۵) years, and ۵۷.۲% (۱۱۱ out of ۱۹۴) were women. Mean survival time was ۲۹۴.۷ ± ۹.۹۲۴ days. Pervious history of myocardial infarction (MI) [۲.۱۴۱ (۱.۱۰۱-۴.۱۶۱)] increased the risk of cardiovascular hospitalization. Elevated blood levels of potassium [۲.۲۶۴ (۱.۴۳۸-۳.۵۶۴)] was found to be a risk factor for all-cause and cardiovascular mortality. Moreover, there was a reverse relationship between body height [۰.۹۴۲ (۰.۸۸۸-۰.۹۹۹)] and cardiovascular death. Patients with opium addiction [۴.۰۴۹ (۱.۳۱۰-۱۲.۵۱۶)] are at a higher risk of cardiovascular mortality. Lower levels of LDL-C [۰.۹۷۷ (۰.۹۶۰-۰.۹۹۶)] and living in rural areas [۳.۰۵۲ (۱.۰۳۹-۸.۹۶۴)] increased all-cause mortality levels. Lack of pervious history of chronic obstructive pulmonary disease (COPD) decreased cardiovascular hospitalization [۰.۲۶۵ (۰.۰۶۲-۱.۱۲۲)].CONCLUSION: In our study, serum potassium, LDL-C, and uric acid levels in patients with HF were identified as prognostic factors. The height of patients, which can be an indicator of the functional state of their respiratory system, and the history of COPD were also recognized as prognostic factors. Opium use and rural living were identified as social factors influencing patients' prognosis.

کلیدواژه ها:

Systolic Heart Failure ، Prognostic Factors ، Follow-Up Study