Cu/PDA/CCE as A Sensitive Electrode for Concurrent Determination of Ascorbic Acid and Folic Acid

Herein, the electrooxidation of ascorbic acid and folic acid, as two essential vitamins, on the surface of the carbon ceramic electrode modified by polydopamine and copper (Cu/PDA/CCE) was investigated. Poly dopamine was fabricated by applying electro deposition conditions. Initial electrochemical characteristics were performed to study the behavior of the fabricated electrode for simultaneous detection of two biomolecules. From voltametric studies using the developed electrode, two separated anodic peaks for folic acid and ascorbic acid were found promisingly for concurrent detection of the compounds. Linear calibration diagrams were obtained in the range of ۰.۵ to ۳۶۰ μM and ۰.۸۳ to ۳۸۰ μM with detection limits of about ۰.۰۳۱ and ۰.۰۵۷ μM for folic acid and ascorbic acid, respectively. The developed electrode was applied in human urine sample analysis with satisfying results

کلیدواژه ها:

Folic acid: ، ascorbic acid ، : Carbon ceramic: ، Concurrent determination: ، Polydopamine