Synthesis and Characterization of Cross-linked Nanocomposites Chitosan/Tripolyphosphate/Triphenyl tin Chloride-Phosphorus Triamide

Organotin compounds have received much attention due to their various applications in biological, catalytic and industrial fields. Coordination chemistry of tin (IV) complexes with phosphoramide ligands is of interest due to its antitumor and antibacterial activity [۱]. Chitosan (CS), the second most plentiful natural polysaccharide next to cellulose, has valuable characteristics including biocompatibility, nontoxicity an biodegradability. Tri-polyphosphate (TPP) is considered as an ionic crosslinker because of its performance benefits, simple process control and high safety.The role of chitosan ion cross-linked TPP in the preparation of nanoparticles showed that the degree of cross-linking of CS/TPP nanoparticles is related to the particle size as well as the antimicrobial activity of nanoparticles, which is the basis for controlling CS/TPP nanoparticle preparation. The application of chitosan metal complexes is focused on the separation or removal of metal ions, dyeing, catalysis, water treatment and many other industrial processes [۲]. However, little research has focused on their biological activities. Due to the importance of tin complexes with biological activity and CS/TPP composites, we became interested in synthesis of tin (IV) complexes with phosphoramide ligand, and as well as CS/TPP/tin-phosphoramide nanocomposites.In this study, first a new tin(IV)–Phosphoramide complex with formula (C۶H۵)۳SnCl[P(O)(NH-CH۲-C۶H۵)۳] was synthesis, and the crystal structure was determined. In the crystal structure, the tin(IV) environment adopts a distorted trigonal bipyramidal geometry. Afterward, composite of (CS/TPP) will be prepared, and tin(IV)–Phosphoramide complex load on composit. The complex and CS/TPP/tin-Phosphoramide nanocomposite were characterized by using XRD, SEM, TGA, ۱۳C, ۳۱P, ۱H NMR, FT-IR spectroscopy.