Risk Factors of Tuberculosis Treatment Failure among Tuberculosis Patients in Khuzestan Province: A Retrospective Cohort Study
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 178
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شناسه ملی سند علمی:
JR_IEM-7-4_002
تاریخ نمایه سازی: 8 اسفند 1400
چکیده مقاله:
Background: Tuberculosis (TB) is an infectious and communicable disease and one of the top ten causes of death throughout the world. Monitoring and evaluating TB treatment outcomes provides the required data for taking the necessary measures to control TB. Thus, this study was carried out to find determinants of treatment failure among patients with smear-positive pulmonary TB in Khuzestan province during ۲۰۰۶-۲۰۱۴
Materials & Methods: This retrospective cohort study was conducted over a ۹-year period in Khuzestan province. Predictors of treatment failure were analyzed using multivariate logistic regression
Findings: Among ۵۳۴۲ patients, the cumulative incidence of unsuccessful TB treatment was ۱.۸۵%. More than half of TB patients (۵۹.۲%) enrolled in this study were male, and most of them were living in urban areas (۷۹.۸%). Significant predictors of treatment failure were age (p=·۰۰۱), weight (p= ·۰۳۹), number of delayed days in diagnosis (p=·۰۱), isoniazid resistance (p≤·۰۰۱), and number of bacilli in patients` sputum at the beginning of treatment (p≤·۰۰۱).
Conclusion: In this study, the rate of successful treatment was quite high; nevertheless, new cases of treatment failure could be prevented with special efforts such as prompt diagnosis and precise follow-up under Direct Observation Treatment Short course (DOTS) strategy.
کلیدواژه ها:
نویسندگان
Sayed Ali Mousavi
Department of Public Health, Shoushtar Faculty of Medical Science, Shoushtar, Iran
Mohammad Fararouei
HIV/AIDS Research Center, Shiraz University of Medical Science
Hadi Rashidi
Department of Epidemiology, Shiraz University of Medical Sciences, Shiraz, Iran
Saeideh Shojaei
Department of Epidemiology, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Faeze Bahrami Astaraki
Student of Nutrition science, Shoushtar University of Medical Science
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