Background and Aim: Traumatic Brain Injury (TBI) is an essential cause of morbidity and mortality worldwide. TBI patients frequently encounter lung complications, such as Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS), which is associated with poor clinical outcome because hypoxia causes additional injury to the brain. This study aimed to evaluate the frequency of ALI in patients with TBI and its consequences.
Methods and Materials/Patients: In this descriptive cross-sectional study, data from all records of patients admitted to Poursina Hospital’s ICU (emergency and neurosurgery ICU) in ۲۰ ۱۸-۲۰۱۹ were used. The evaluated data included age, gender, type of head trauma mechanism, kind of brain injury based on CT scan findings, the severity of brain injury based on Glasgow Coma Scale (GCS), underlying diseases, mean head AIS score, the number of pack cell units injected, as well as bilateral pulmonary infiltration in favor of ALI and brain injury.
Results: Only ۸۱ of the ۵۵۷ TBI cases met the inclusion criteria of the present study. The highest frequency of ALI following TBI was observed on the first day of hospitalization, in men (۰.۴۱%) in the age group of ۴۰-۵۰ years (۷%) with severe brain damage (۶%) and subdural hematoma (۱۲%), following a motorcycle accident, cars, as well as on the third day of hospitalization were seen in men (۴۳.۸%) with the age group of ۲۰-۳۰ years (۵۵%) with severe brain damage (۴۲%) and intra-parenchymal bleeding (۵۷%), following a motorcycle accident. In addition, no significant correlation was detected between the incidence of ALI and mortality, the duration of hospitalization, GCS, mean head AIS score, or the extent of received blood units in our study.
Conclusion: According to the obtained findings, men aged between ۲۰ and ۳۰ years with severe cerebral injury, epidural hematoma and a motorcycle accident presented the highest rate of progression toward ALI in the first to third days of hospitalization.