Soli d-state kin etics calculation of a new sy nthesized oxovanadium(IV) com plex using differential scanning calorimetry

Solid-state kinetic studies of oxovanadiu m comple x calculate of kinetic parameters (activation energy, frequency factor, r eaction model) using differential scanningcalorimetry (DSC) technique, condition of non-isother mal and with model-fitting of direct differential method. Experimentally, solid-s tate kinetic s was studied either isothermally or nonisot hermally. T hese method s generally fall into o ne of two categories: m odel-¿tting and model-free. Solid-state kin etics can be studied with thermal analytical methods for example by differential scanni ng calorimetry (DSC). [۱].Solid-sta te kinetic studies have appeared in the pharmaceutical literature ov er many years. Before the discovery of insulin and its c linical trials for treating diabetes mellitus (DM) , inorganic salts of vana dium have long be en known to act as orally viable mi mics [۲]. Since insulin is not orally a ctive, great effort has therefor been made to synthe size oxova nadium(IV) complexes of organic ligands of high biological acti vity (hydro/lipophilicity) therefore we have synthesized a new oxovanadium complex and during our research discovered this complex is a high- energy material by thermal analysis technique (DSC).

کلیدواژه ها:

Solid-state kinetic ، Diffrential s canning calo rimetry ، Di rect differential method