Kinetic study of the oxidation of epinephrine by digital sim ulation of cyclic vol tammograms

Epinephrine is one of the im portant catecholamine , plays a central role during phy sical or mental stress and also stimulates a series of actions of the sym pathetic nervous syste m (SNS) known as the “flight or figh t response” [۱]. It prepares the body for action in perceived emergency situatio ns, boostin g the supply of oxyge n and energy giving g lucose to the brain and muscles [۲]. The catechol group of epinephrine can be oxidized chemically or electroc hemically to its o-benzoquinones as a good Michael acceptor that can be attacked by side chain amine g roup as nucleophile via an intra molecular addition reaction. Alth ough the chemical or electrochemical oxidation path-way of catecholamines ar e well known, the kinetics of their cyclization reactions has been little investigate d [۳].

کلیدواژه ها:

kinetic study ، epi nephrine ، digital simulation ، cyclic voltammetry