Investigation of the Relationship between Serum Leptin levels and Nausea and Vomiting of Pregnancy

سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 184

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_NMCJ-7-4_008

تاریخ نمایه سازی: 22 آذر 1400

چکیده مقاله:

Background: Worldwide, half of women suffer from nausea and vomiting in early pregnancy which generally continues to the ۲۰th week of pregnancy. Although pathogeneses of nausea and vomiting of pregnancy as well as hyperemesis gravid arum are still unknown, some believe that  nausea and vomiting of pregnancy is likely related to maternal serum leptin level. Objectives: This study aimed to examine the relationship between leptin and pregnancy nausea and vomiting. Methods: In this case-control study, ۴۵ pregnant women at first and second trimesters were selected through convenient sampling. Mothers’ blood samples were taken in the ۶th, ۱۲th, ۱۵th, and ۲۰th weeks of pregnancy. The participants were devised into healthy, without nausea, (۲۴) and with nausea and vomiting groups (۲۱). The relationship among the variables was analyzed using independent t-test, Pearson correlation, regression tests, and Lambda statistic (P value <۰.۰۵). Results: The mean age of the participants was ۲۷.۴۷±۵.۵۵ years, and Body Mass Index (BMI) was found to be ۵.۴۵۸±۲۶.۵۷. There was no significant difference between groups in this regard. Based on results, changes in maternal serum leptin had significant correlation with nausea and vomiting of pregnancy (p<۰.۰۴), meaning that the mean of leptin changes in patients with nausea and vomiting was significantly lower. Moreover, serum leptin at first and second trimesters of pregnancy did not have significant correlation with nausea and vomiting (p=۰.۵ and ۰.۳, respectively). Conclusion: With regard to leptin peak level at second trimester of pregnancy, leptin changes at first and second trimesters can be a good index to predict the nausea and vomiting of pregnancy. Thus, further domestic studies are required in this respect.  

کلیدواژه ها:

نویسندگان

marzieh faghani aghoozi

MSc. Dept. of midwifery, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran

Sanaz Fayazi

MSc. Dept. of midwifery, School of Nursing and Midwifery, Zanjan University of Medical Sciences, Zanjan, Iran

Malihe Amerian

MSc. Dept. of midwifery, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran

Amir Hamta

PhD. Dept. of Social Medicine, Assistant Professor, School of Nursing and Midwifery, Qom University of Medical Sciences, Qom, Iran

Najmeh Tehranian

PhD .Dept. of Midwifery and Reproductive Health, Medical Sciences Faculty, Tarbiat Modares University, Tehran, I.R.Iran

Fahimeh Ramezani Tehrani

Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Nazari S, Nazari S, Shayan A, Shobeiri F, Tabesh RAN. ...
  • Pakniat H, Memarzadeh MR, Azh N, Mafi M, Ranjkesh F. ...
  • Austin K, Wilson K, Saha S. Hyperemesis Gravidarum. Nutr Clin ...
  • Verberg M, Gillott D, Al-Fardan N, Grudzinskas J. Hyperemesis gravidarum, ...
  • Motlagh AA, Garshasbi E, Kazemnezhad A, Motlagh AA, Lamiyan M. ...
  • Piri S. Nousea and vomiting of pregnancy. Iranian Journal of ...
  • Köşüş N, Köşüş A, Hızlı D, Turhan N. Appetite hormones ...
  • Niemeijer MN, Grooten IJ, Vos N, et al. Diagnostic markers ...
  • Alizzi F, Abbas WAJA, Fawzi H. Assessment of the role ...
  • London V, Grube S, Sherer DM, Abulafia O. Hyperemesis Gravidarum: ...
  • Shafti V, Zakerihamidi M. Relationship between Nausea and Pregnancy Vomiting ...
  • Herrell HE. Nausea and Vomiting of Pregnancy. Am Fam Physician. ...
  • Hussein KS. Thyroid Functions with Cases of Hyperemesis Gravidarum in ...
  • Al-Basam AN, Mohammad A. The Association between Maternal Ghrelin Hormone ...
  • Huxley RR. Nausea and vomiting in early pregnancy: its role ...
  • Zhang Y, Li Z, Zhang L, et al. Association between ...
  • Shishehgar F, Payman A. Characteristics of nausea and vomiting in ...
  • Nikibakhsh A, samani LN, Keshavarz M, Hoseini F. Incidence and ...
  • Ali MAH, Naser HA, Saleh IM, Hasan RAM. Comparison of ...
  • Yang MJ. Interrelationships of Maternal Serum Leptin, Body Mass Index ...
  • Al-Rasheid N, Gray R, Sufi P, et al. Chronic Elevation ...
  • Ezzaddin F, Tahseen F, Ahmed SN. Evaluation of serum leptin ...
  • Ârdakani JM. Effect of metformin on the levels of leptin ...
  • Orabi HAHE, Sabry IM, Allah AMA, Alkhalek AAA. Assessment of ...
  • Kuo S-H, Yang Y-H, Wang R-H, Chan T-F, Chou F-H. ...
  • Gungor S, Gurates B, Aydin S, et al. Ghrelins, obestatin, ...
  • Zhou Q, O’Brien B, Soeken K. Rhodes index of Nausea ...
  • Albayrak M, Karatas A, Demiraran Y, et al. Ghrelin, acylated ...
  • Demir B, Erel C, Haberal A, et al. Adjusted leptin ...
  • Aka N۱, Atalay S, Sayharman S, et al. Leptin and ...
  • Chou F, Chan T, Chin C, Chen Y, Shen C, ...
  • Kosus A, Eser A, Kosus N, Usluogullari B, Hizli D. ...
  • Unsel N, Benian A, Erel C. Leptin levels in women ...
  • Lee J, Lee K-H, Kim M-S, et al. The correlation ...
  • Arslan E, Cengiz L, Arslan M. Thyroid function in hyperemesis ...
  • نمایش کامل مراجع