The Comparison of Cimifugol and Salvigol on Night Sweats in Postmenopausal Women: a Single Blind Clinical Trial Study

Background & aim: The purpose of this study is to compare the effects of Cimifugol and Salvigol capsules on night sweats in postmenopausal women.Methods: This research was a randomized clinical trial that was performed on ۸۰ postmenopausal women. The participants were assigned into two groups of ۴۰ peoples (Cimifugol) and (Salvigol). Cimifugol was ۶.۵ mg and consumed ۱ times per day and salvigol ۱۰۰ mg in the amount of ۳ timed per day. They used the medicine for ۲ months. Wiklund vasomotor symptom scale was used for recording the intensity and frequency of night sweats. This scale was completed in each group before the intervention and then every week for ۸ weeks after the intervention. SPSS version ۲۰ was used to analyze the data. The significance level of the tests was considered to be less than ۵%.Results: The mean and standard deviation of the number of sweats as well as its duration in Salvigol group before and at the end of the eighth week after the intervention were (۸.۹۳±۶.۳۵۰), (۶.۱۵±۴.۳۹۴) and (۲.۵۳±۱.۱۳۲), (۱۹۵±۱.۱۰۸), respectively. Salvigol was effective on the frequency of night sweats in different weeks (P <۰.۰۰۱), but in Cimifugol group no significant difference was seen in the frequency and duration of night sweat during the time (P >۰.۰۵).Conclusion: Based on the results, the use of salvigol in the treatment of menopausal sweating is recommended.

کلیدواژه ها:

Menopause ، Sweats ، Salvigol ، Cimicifuga