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Therapeutic potential of Juglans regia L. leaf extract against diabetic retinopathy in rat

محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 20، شماره: 11
سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 247

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لینک ثابت به این مقاله:
https://civilica.com/doc/1295642

شناسه ملی سند علمی:

JR_IJBMS-20-11_014

تاریخ نمایه سازی: 28 مهر 1400

چکیده مقاله:

Objective(s): Oxidative stress has a pivotal role in the pathogenesis of diabetic retinopathy (DR). Juglans regia L. (JRL) leaf extract has hypoglycemic and antioxidative properties. This study aimed to determine the ameliorative effects of JRL against diabetic retinopathy. Materials and Methods: The DR rat model was generated by injection of streptozotocin (STZ). A subset of the diabetic rats received JRL or metformin after the onset of hyperglycemia. Histopathology and immunohistochemistry of apoptotic and inflammatory factors were assessed along with biochemical assessments of lipid peroxidation and antioxidant status. Results: Lipid peroxidation level and catalase activity significantly improved after JRL consumption (PPP Conclusion: JRL leaf extract exert protective effects against diabetic retinopathy.

کلیدواژه ها:

Antioxidant ، Apoptosis ، Diabetic retinopathy ، Hyperglycemia ، Inflammation ، Juglans regia L. leaf

نویسندگان

Davood Nasiry

Anatomy Department, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran

Ali Reza Khalatbary

Molecular and Cell Biology Research Center, Department of Anatomy, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

Hassan Ahmadvand

Department of Biochemistry, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran

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  • Klein BE. Overview of epidemiologic studies of diabetic retinopathy. Ophthalmic ...
  • Joussen AM, Poulaki V, Le ML, Koizumi K, Esser C, ...
  • Guzman DC, Olguín HJ, García EH, Peraza AV, de la ...
  • Tarr JM, Kaul K, Chopra M, Kohner EM, Chibber R. ...
  • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. ...
  • Lim TK. Edible medicinal and non-medicinal plants. Springer Dordrecht Heidelberg ...
  • Sorber DG, Kimball MH. Use of ethylene in harvesting the ...
  • Pereira JA, Oliveira I, Sousa A, Ferreira IC, Bento A, ...
  • Pereira JA, Oliveira I, Sousa A, Valentão P, Andrade PB, ...
  • Zhao MH, Jiang ZT, Liu T, Li R. Flavonoids in ...
  • Almeida IF, Fernandes E, Lima JL, Costa PC, Bahia MF. ...
  • Erdemoglu N, Küpeli E, Yeşilada E. Anti-inflammatory and antinociceptive activity ...
  • Carvalho M, Ferreira PJ, Mendes VS, Silva R, Pereira JA, ...
  • Rather MA, Dar BA, Dar MY, Wani BA, Shah WA, ...
  • Noumi E, Snoussi M, Hajlaoui H, Valentin E, Bakhrouf A. ...
  • Javidanpour S, Fatemi Tabtabaei SR, Siahpoosh A, Morovati H, Shahriari ...
  • Jelodar G, Mohsen M, Shahram S. Effect of walnut leaf, ...
  • Asgary S, Parkhideh S, Solhpour A, Madani H, Mahzouni P, ...
  • Mohammadi J, Delaviz H, Malekzadeh JM, Roozbehi A. The effect ...
  • Hosseini S, Huseini HF, Larijani B, Mohammad K, Najmizadeh A, ...
  • Hosseini S, Jamshidi L, Mehrzadi S, Mohammad K, Najmizadeh AR, ...
  • Pitschmann A, Zehl M, Atanasov AG, Dirsch VM, Heiss E, ...
  • Vandendool H, Kratz PD. A generalization of the retention index ...
  • Gong CY, Lu B, Hu QW, Ji LL. Streptozotocin induced ...
  • Tzeng TF, Liou SS, Tzeng YC, Liu IM. Zerumbone, a ...
  • Mihara S, Uchiyama M. Determination of malonaldehyde precursor in tissues ...
  • Aebi H. Catalase in vitro. Methods Enzymol ۱۹۸۴; ۱۰۵:۱۲۱-۱۲۶ ...
  • Jiang Y, Walker RJ, Kern TS, Steinle JJ. Application of ...
  • Amaral JS, Seabra RM, Andrade PB, Valentao P, Pereira JA, ...
  • Hosseinzadeh H, Zarei H, Taghiabadi E. Antinociceptive, anti-inflammatory and acute ...
  • Kowluru RA, Chan PS. Oxidative stress and diabetic retinopathy. Exp ...
  • Anderson RE, Rapp LM, Wiegand RD. Lipid peroxidation and retinal ...
  • Wu Y, Tang L, Chen B. Oxidative stress: implications for ...
  • Pacher P, Obrosova IG, Mabley JG, Szabó C. Role of ...
  • Solar A, Colarič M, Usenik V, Stampar F. Seasonal variations ...
  • Gawlik-Dziki U, Durak A, Pecio Ł, Kowalska I. Nutraceutical potential ...
  • Eidi A, Moghadam JZ, Mortazavi P, Rezazadeh S, Olamafar S. ...
  • Kowluru RA, Koppolu P, Chakrabarti S, Chen S. Diabetes-induced activation ...
  • Nagai N, Izumi-Nagai K, Oike Y, Koto T, Satofuka S, ...
  • Zheng L, Howell SJ, Hatala DA, Huang K, Kern TS. ...
  • Krady JK, Basu A, Allen CM, Xu Y, LaNoue KF, ...
  • Borrie SC, Duggan J, Cordeiro MF. Retinal cell apoptosis. Expert ...
  • Li YH, Zhuo YH, Lü L, Chen LY, Huang XH, ...
  • Salimi M, Majd A, Sepahdar Z, Azadmanesh K, Irian S, ...
  • Alshatwi AA, Hasan TN, Shafi G, Syed NA, Al-Assaf AH, ...
  • Hasan TN, B LG, Shafi G, Al-Hazzani AA, Alshatwi AA. ...
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