A review on medicines used for treatment of SARS-CoV-۲

Background and Aim : SARS-CoV-۲ or CoVid۱۹ pandemic caused a huge mortality and fear all over the world for so long. Finding a cure or prophylaxis is necessary to reduce global panic as well as mortality.on the other side the approach for finding an effective vaccine seems to be not successful so far.Methods : Over ۲۰ articles have been studied and medicines which were recently used to cure and cause relief were extracted. some of them were clinical and mostly were used in vitro in which the effect of the would be discussed carefully an addition to the role of each drug.Results : It seems that the following drugs could be kind of effective; Chloroquine and hydroxychloroquine, remdesivir, favipiravir, Ritonavir, Tocilizumab, Depo-medrol, Arbidol, Nitazoxanide, Ivermectin, Glucocorticoid and JAK inhibitors.Conclusion : Despite all the efforts and large use of antiviral and anti-inflammatory medicines, there is no promising and proven treatment. Most of the drugs above are studied in vitro and there is no evidence of being successful in clinical trials. so more studying and investigation on other drugs or probable vaccine is essential.

کلیدواژه ها:

SARS-CoV-۲ ، treatment ، antiviral drugs ، RNA virus ، infectious genome