The Role of Ureaplasma urealyticum bacteria in infertile men

Background and Aim : Ureaplasma urealyticum bacteria is one of the most important microorganisms due to infertility. The aim of this study is to test the prevalence of U. urealyticum in infertile men. The patients that arrive to infertility clinics (Royan Institute in Tehran) with the semen culture analysis request are asked to fill in a questionnaire about infertility smear collection.Methods : In this case control study presence of U. urealyticum were analyzed in tested men. we have compared ۴۰ infertile males with unexplained infertility and ۴۰ normal men with male factor as a control case group. The semen samples were sent to microbiology laboratory for culture and Selection of bacteria. The information were analyzed with SPSS software by frequency, chi-square & T-test Method .Results : The average age in patients and control groups were ۳۱.۸۷+۵.۲۲ and ۳۱.۴۵+۵.۸۱ the value of U. urealyticum cases were ۱۱(۲۷.۵%) and in normal men were ۴(۱۰%). (P=۰.۰۴۵) then we have found statistically significant differences in the U. urealyticum frequency of the patients. We have not found statistically significant relations between premature ejaculation and infertility. We have not found statistically significant relations between educational levels, ages, and marriage age, Duration of infertility, testis pain, smoking and infertility.Conclusion : We have shown a significantly Ureaplasma urealyticum infections increase in the infertile men. The similarities between this study and the results obtained by others are limited and it may be due to different cultural and normal values in various societies. Though statistically significant due to limited number of subjects, however the difference observed in the prevalance of infection between cases and controls indicates an association between Ureaplasma urealyticum infection and infertility. So, it is suggested to check up those patient with unexplained infertility, for genital micro-organisms infections, and if positive, to control the rate of infertility with a suitable and cost effective therapy