Study of bacterial infection frequency in burn patients at a burn hospital in Iran

Background and Aim : Wound infections are common problems in burn hospitals. Development of infections in burn wound is serious because of their effects on the course of the disease and patient outcomes. Many wound patient die as a result of infection during their hospital courses. The rate of infection in burn cases is extremely high in developing country. For this reasons we carried out study of the bacteriological profiles and a comparison of antimicrobial resistance patterns of these, over a period of one year.Methods : : from March ۲۰۱۷ to April ۲۰۱۸, ۱۵۰۰ sample from Swabs and wound biopsy were included in this study. Identification of isolates was performed according to conventional bacteriological methods. The antibiotic susceptibility test was performed by disk diffusion method (Kirby – Bauer) according to Clinical Laboratory Standards Institute guidelines.Results : ۹۵۷(۶۳.۸%) of ۱۵۰۰ samples included of bacterial infections that were from different wards. ۸۳.۹% of isolates were gram negative and ۱۶.۱% of isolates were gram positive. the highest rate of infections were from ICU (۵۰.۲%) and the lowest were from restoration (۶.۶%). The commonest gram negative bacteria were Acinetobacter baumannii (۳۴.۷%) and Pseudomonas aeruginosa (۲۹.۶%). Staphylococcus aureus (۱۰.۲%) was the commonest gram positive bacteria. ۵۰.۷% of isolates were multi-drug resistant. The most resistant isolates were Acinetobacter baumannii and Pseudomonas aeruginosa. Between A.baumannii isolates the highest and the lowest antibiotic resistance were to ceftazidime (۹۵.۲%) and tobramycin (۵۸.۲%). Among P.aeruginosa the highest and the lowest antibiotic resistance were to ciprofloxacin (۹۱.۹%) and amikacin (۵۷.۹%). Among S.aureus the highest and the lowest antibiotic resistance were to Penicillin (۶۳.۲) and vancomycin (۰%).Conclusion : High prevalence of burn wound infections and presence of multidrug resistant bacteria in burn patients suggest strong surveillance of burn infections and develop strategies for antimicrobial resistance control and treatment of infectious complications.

کلیدواژه ها:

antibiotic resistance ، burn ، infection