Emergence of Vancomycin-Resistant Staphylococcus aureus in the Southwest of Iran

سال انتشار: 1398
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 252

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_IEM-5-4_002

تاریخ نمایه سازی: 25 تیر 1400

چکیده مقاله:

Aims: Following the emergence of methicillin-resistant Staphylococcus aureus (MRSA) isolates, the use of other antibiotics especially vancomycin in S. aureus infections has become inevitable, leading to the emergence of vancomycin-resistant S. aureus (VRSA) strains, which is considered as a major public health concern. This study aimed to determine the vancomycin susceptibility patterns of S. aureus clinical isolates in order to evaluate the current status of vancomycin resistance in the southwest of Iran.Materials & Methods: In this study, ۱۰۰ S. aureus clinical strains were collected from the hospitals of Khuzestan province in the southwest of Iran. Next, antibiotic susceptibility, vancomycin resistance, and the presence of mecA, vanA, vanB, vanC, and vanD genes were investigated in these isolates.Findings: It was found that ۱ and ۲ isolates were vancomycin-intermediate S. aureus (VISA) and VRSA, respectively. All three strains showed methicillin-resistance pattern and carried mecA gene. vanA gene was detected in VRSA strains, whereas vanB, vanC, and vanD genes were detected in none of these isolates.Conclusion: This study findings could be alarming regarding the emergence and spread of VRSA strains; therefore, the principles of infection control should be employed in the healthcare systems to prevent the spread of VRSA strains in healthcare facilities.

نویسندگان

Vedad Al-Khamis

MSc, Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran

Seyedeh Elham Rezatofighi

PhD, Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran

Hossein Motamedi

PhD, Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran