From Drug Resistance to Pathogenesis: Insights into Pseudomonas and Acinetobacter as bacterial pathogens

P. aeruginosa and A. baumannii are the most widely recognized non-lactose-maturing gram-negative pathogens. In the last decade, these two species have become prevalent agents of hospital infections. It is due to their developed high antimicrobial resistance. The treatment of diseases caused by these species has become muddled as a result of their multi-drug resistance factor. P. aeruginosa and A. baumannii are both known for their ability of immunity to antibacterials, their capacity to procure by flat quality exchange, plasmids, and transposons encoding resistance determinants. We can employ anti-infection agents in curing irresistible illnesses and, empower the use of the best choice of antimicrobial therapy procedures for the elderly, powerless and immune-depressed patients. These two species are responsible for contamination in patients in ICU. Their anti- microbial factor is a worrisome factor to humans. Hence, studies tending to conceivable intend to minimize and inevitably anticipate anti-infection resistance must be viewed as a need for the future strength of humankind.

کلیدواژه ها:

P. aeruginosa ، A. baumannii ، pathogen ، Disease ، Anti- microbial ، Anti-infection