Assessment of Different Manifestations of Known Cases of Behçet’s Disease

 Background: Behçet’s disease (BD) is a multi-system inflammatory vascular disorder with auto immunity background. It is a genetic disease that may be affected by environmental factors. Behçet’s disease may involve different organs like urogenital, skin, eyes and gastrointestinal system. According to geographic area and genetic predisposition, prevalence of the disease is different. The aim of this study was the evaluation of some clinical features of muco-cutaneous lesions of Behcet,s disease in ۲۰۱۸. Materials and Methods: This cross-sectional study was done on ۴۳ patients with Behçet’s disease (۲۴ men, ۱۹ women). Data about age, sex, duration of the disease, taking medicine was collected. The self-reported questionnaire was completed by participations. Skin manifestations, genital and ocular involvement were alsodocumented. Results: The male to female ratio was ۱.۲۶/۱. Oral aphthous commonly localized on the lips. The percent for ocular involvement and skin lesions were ۷۶%,۴۸% respectively. There was a statically significant correlation between ocular lesions and age. Also relationship between skin lesions and frequency of oral aphthous per year was meaningful too. There was a significant relationship between incidence of ocular lesions and incidence of skin lesions.   Conclusion: Oral aphthous as the most popular manifestation of BD is the hallmark of diagnosis. Thus, patients with oral aphthous require close surveillance for other manifestations of BD for timely diagnosis and refer to Rheumatologist.

کلیدواژه ها:

Stomatitis ، Aphthous ، Behcet Syndrome ، eye manifestations ، genitalia ، skin manifestations