Perturbation Effect of Fiducial Marker on ۳D Dose Distribution in External Surrogates Radiotherapy
محل انتشار: مجله فیزیک پزشکی ایران، دوره: 18، شماره: 2
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 174
فایل این مقاله در 10 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IJMP-18-2_003
تاریخ نمایه سازی: 6 اردیبهشت 1400
چکیده مقاله:
Introduction: Tumor motion is a challenging issue in radiotherapy, which complicates the process of tumor delineation, localization, and dose delivery. External surrogate radiotherapy is one of the available strategies that provides motion dataset for a consistent prediction model to track tumor motion using internal-external markers. Regarding this, the present study was conducted to investigate the effect of implanted fiducial on ۳D uniform dose distribution. Material and Methods: For the purpose of the study, a Monte Carlo code was utilized to simulate clip with different dimensions and material structures against four therapeutic beams. Moreover, a combinational clip made of golden and covered by polymethyl methacrylate (PMMA) was proposed to be used with lower dose perturbation. Finally, it was proposed to implant a clip outside tumor volume at specific distances from tumor site to keep dose uniformity on tumor volume. To investigate this issue, the correlation coefficient parameter was calculated as the metric among the motion dataset of tumor and clip. Results: Based on the results, dose perturbation caused by implanted clip was remarkable at hadron therapy depending on its size and material, mainly at the downstream part of the clip. Conclusion: As the findings indicated, the golden marker covered with PMMA could remarkably reduce dose perturbation. The most important concern in this domain is the presence of a possible correlation between tumor motion and motion of the clip implanted outside the tumor volume. The results of the correlation coefficient revealed a close relationship between tumor motion and clip motion.
کلیدواژه ها:
نویسندگان
Ahmad Esmaili Torshabi
Faculty of Sciences and Modern Technologies, Graduate University of Advanced Technology, Kerman, Iran
Masoud Taghipour
Faculty of Sciences and Modern Technologies, Graduate University of Advanced Technology, Kerman, Iran
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :