A Novel Nanomagnetic Catalyst for the Synthesis of 4H-Chromenes

4H-chromene rings are an important class of oxygen heterocyclic that display a broad spectrum of interesting biological activities such as anti-bacterial, anti-cancer, anti-coagulant and anti-proliferative properties [1-4].Herein, a new Ag/Fe3O4@starch nanocomposite was synthesized and used as a efficient catalyst for the synthesis of 4H-chromene derivatives using the reaction of benzaldehyde derivatives, malononitrile and cyclo-1,3-diketones (Scheme 1). The method of preparation of this catalyst is simple and has efficiency and short time in synthesis of various chromene derivatives. The remarkable magnetic properties of the nanocomposite made it easy to separate the catalyst from the reaction mixture without significantly reducing the catalytic properties of the nanocomposite.

کلیدواژه ها:

Nanocomposite ، Starch ، Cross-Link ، Iron Oxide ، Silver ، 4H-chromenes