Theoretical Study of Free Energies of Electron Transfer of Third-Generation Cephalosporin Antibiotics with Fullerenes in Nanostructure of [R].Cn Supramolecular Complexes

In this study, the number of carbon atoms in the fullerenes was used as an index to establish a relationship between the structures of Cefotaxime, Ceftriaxone and Cefoperazone, as well-known third-generation cephalosporins antibiotics and fullerenes Cn (n=60, 70, 76, 82 and 86). The relationship between the number of carbon atoms and the free energies of electron transfer (DGet(1) to DGet(4)) are assessed using the Electron transfer equation for these supramolecular [R].Cn complexes. The calculations are presented for the four reduction potentials (Red.E1 to Red.E4) of fullerenes Cn. The results were used to calculate the four free-energies of electron transfer (DGet(1) to DGet(4)) of supramolecular complexes for fullerenes C60 to C300.