A green and highly effective protocol for the synthesis of N,N′-alkylidene bisamides using saccharin-N-sulfonic acid

A green and highly effective solvent-free protocol has been reported for the synthesis of N,N′-alkylidene bisamides via the reaction of arylaldehydes (1 eq.) with primary amides (2 eq.) in the presence of saccharin-N-sulfonic acid (SaSA) as a solid-acid catalyst. The mentioned compounds have been obtained in high yields and short reaction times.

کلیدواژه ها:

N ، N′-Alkylidene bisamide ، arylaldehyde ، primary amide ، saccharin-N-sulfonic acid (SaSA) ، solid acid ، solvent-free