افشین رشید
اُستادیار ؛ عضو هیات علمی دانشگاه آزاد اسلامی واحد علوم و تحقیقات تهران
492 یادداشت منتشر شدهReview of Genome Nano Biochip (structure and Function of Genome Nanochip)

Note: The Genome Nano biochip , a bioelectronic and microarray nano- device , widely performs genomic, proteomic and functional analysis on a large scale.
Genome Nano biochip mainly includes three types: DNA microarray , protein microarray, and microfluidic chip. By integrating microarray and microfluidic systems, a total micro-nano analysis system is produced, often referred to as a lab-on-a-chip (LOC). Advances in nanotechnology have continuously reduced the size of biochemistry , which in turn has reduced the cost of production and increased its high throughput capability. Due to the advantages of low cost, high power and nano miniaturization, this technology has great potential. The biggest advantage of DNA arrays is its high speed and power, and it is used in various genomic applications, including analysis by electric nanoparticles, Genome Nano biochip . Genome Nano biochip chips , especially functional microarrays , is used to study basic biological properties such as investigating the interaction of cells or other molecules. Genome Nano biochipis able to perform various types of chemical and cellular analysis, isolation and reaction. Genomenano biochip is one of the fastest growing areas of microfabrication and the development of nanotechnology and many technologies to develop applications in a wide range of disciplines including analysis and detection in cells by Nano particles are used.

Genome Nano biochip is used for various biomolecule assay applications. which includes many biomolecular nano-sensing techniques. Genome Nano biochips are mainly designed to detect antibodies and infectious diseases (viruses, fungi, parasites, etc.). and generally detect and identify a wide variety of biomolecules in a sample - including, but not limited to DNA, RNA, antibodies and antigens, enzymes, bacteria, fungi and viruses. Genome Nano biochip has also found special applications in skin-on-a-chip applications.
Conclusion:
Genome Nano biochip , a bioelectronic and microarray nanodevice , widely performs large-scale genomic, proteomic , and functional analysis .