Evaluation of serum zinc changes following the major operations in term neonates who need to major operation

Introduction: This study was aimed to investigation of changes of serum zinc in term neonates who need to major operation. Methods: 59 neonates who need to major operation were studied. All patients underwent major surgical with high stress. The metabolic response to surgery was studied by measuring the serum zinc before and after surgery (24 hours and at discharge time postoperatively). The repeated measure analyze used to test changes of plasma values of zinc, over time. Results: The plasma values of zinc was 89.78±14.50 μg/dl after surgery, 74.95±15.86 μg/dl in 24 hours after surgery and 93.78±14.53 μg/dl at discharge. The plasma values of zinc decreased immediately after surgery that this decline continued until the first 24 hours of operation. Serum zinc concentration decreased significantly at 24 hours at discharge . No significant differences were between two sex groups. Conclusion: Results showed that zinc levels in term neonates who need to major operation were decreased temporary but later returned to normal. It seems that in this patients there is no need for supplementation of zinc along two weeks after operation.

کلیدواژه ها:

Serum zinc ، Full-Term Infant ، Major surgery