Isolation and antibiotic resistance pattern determination of bacteria causing urinary tract infections in patients referred to the central laboratory of Poldokhtar city in Lorestan, Iran

Background and Objectives: Urinary tract infections are one of the most common bacterial infections in humans. Increasing resistance to antimicrobial agents in bacteria is a major problem around the world in treatment of urinary infections. Materials and Methods: In this descriptive study, 2150 urine samples were collected from admitted patients. Urine specimens were cultured in Blood agar and Eosin-methylene blue medium (EMB), then were identified the specimens that were positive in term of culture. Resistance and sensitivity tests of urinary pathogens to conventional antibiotics were evaluated using a standard diffusion method according to CLSI standard. Results: The urine test result was positive in 107 (4.9%) patients of 2150 eligible ones. They were 10.3% male and 79.7% female. The most common pathogens isolated were Escherichia coli (83.2% ), Staphylococcus epidermidis (7.5 %), Citrobacter species (2.8% ), Proteus species (2.8% ), and Klebsiella (2.8% ). The most antibiotic resistance was related to co-trimoxazole (58.1% ) and the Highest sensitivity was related to nitrofurantoin antibiotics (90.1 %) and gentamicin (88% ). Conclusion: The present study showed that Escherichia coli is the most common pathogen causing the urinary tract infection. Due to the high resistance of co-trimoxazole to antibiotics, it is recommended to avoid overuse, as well as is antibiogram tests are essential for treatment of urinary tract infections.

کلیدواژه ها:

urinary tract infection ، pattern of antibiotic resistance ، Escherichia coli