Semi-quantitative segmental perfusion scoring in myocardial perfusion SPECT: visual vs. automated analysis
محل انتشار: مجله پزشکی هسته ای ایران، دوره: 22، شماره: 2
سال انتشار: 1393
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 424
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شناسه ملی سند علمی:
JR_IRJNM-22-2_005
تاریخ نمایه سازی: 21 بهمن 1398
چکیده مقاله:
Introduction: It is recommended that the physician apply at least a semi-quantitative segmental scoring system in myocardial perfusion SPECT. We aimed to assess the agreement between automated semi-quantitative analysis using QPS (quantitative Perfusion SPECT) software and visual approach for calculation of summed stress score (SSS), summed rest score (SRS) and summed difference score (SDS).
Methods: We retrospectively studied 1782 consecutive patients who had undergone two-day stress-rest Tc99m-MIBI myocardial perfusion SPECT. Based on 17-segment 5-scale scoring system, SSS, SRS and SDS were calculated visually and using QPS software.
Results: There was good correlation between visual analysis and QPS software in calculation of SSS and SRS and a fair correlation for SDS. However, there was statistically significant difference between two methods. By Bland-Altman analyses mean value of the differences (estimated bias) differs significantly from 0 on the basis of 1-sample t-test. Based on bias, Precision and 95% limits of agreement, discrepancies between measurements indicate no agreement equally through the range of measurements, so there is a proportional bias. Based on SSS, SRS and SDS ≤3 and SSS, SRS and SDS > 3, there was fair concordance between the visual assessment and automated QPS calculation. Kappa statistics was 0.41 (P<0.001), 0.69 (P<0.001) and 0.25 (P<0.001) for SSS, SRS and SDS respectively.
Conclusion: Although semi-quantification sores by visual and automated analysis is correlated, the agreement assessed by Bland-Altman analysis is not high especially in more extensive perfusion defects. Semi-quantitative automated analysis should be used as a supplement to the visual assessment.
کلیدواژه ها:
نویسندگان
Vahid-Reza Dabbagh Kakhki
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Ramin Sadeghi
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Maryam Torabian-Kakhki
Ferdowsi University of Mashhad, Mashhad, Iran
Maseoud Pezeshki-Rad
Radiology Department, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
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