The current status and future of theranostic Copper-64 radiopharmaceuticals

سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 235

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شناسه ملی سند علمی:

JR_IRJNM-25-1_001

تاریخ نمایه سازی: 21 بهمن 1398

چکیده مقاله:

Copper-64 was produced in large scales and high specific activities in late 1990s’ using compact cyclotrons based by 64Ni(p,n)64Cu reaction and many radiopharmaceuticals developed since then by various groups based on interesting physicochemical and nuclear properties of the radionuclide. The unique emission of beta particles as well as positron particles offers a spectacular real therapeutic/diagnostic ( Theranostic ) radionuclide in nuclear medicine. Although the development of copper-64 radiopharmaceuticals continued with a slower rate in 2010s’ due to availability of 68Ga-tracers, however recent advances in application of therapeutic doses of 64Cu has emerged a new trend in the radiopharmaceutical development based on coppe-64. In this review, recent advances in the copper-64 theranostic radiopharmaceuticals including introduction of new chelating groups with enhanced stability as well as radiolabelling conditions as well as application of simple 64CuCl2 radiopharmaceutical as areal theranostic agent in human subjects are summarized. A proposed strategy for development of peptide based copper-64 radiopharmaceuticals with high and low dose therapeutic applications has been suggested.

نویسندگان

Amir Reza Jalilian

Radioisotope Products and Radiation Technology Section, Department of Nuclear Sciences and Applications, International Atomic Energy Agency (IAEA), Vienna, Austria

Joao Osso Jr

Radioisotope Products and Radiation Technology Section, Department of Nuclear Sciences and Applications, International Atomic Energy Agency (IAEA), Vienna, Austria

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  • Blower PJ, Lewis JS, Zweit J. Copper radionuclides and radiopharmaceuticals ...
  • http://www.nucleonica.net/wiki/index.php title=Decay_Schemes ...
  • Matarrese M, Bedeschi P, Scardaoni R, Sudati F, Savi A, ...
  • Jalilian AR, Mirsadeghi L, Yari-kamrani Y, Rowshanfarzad P, Kamali-Dehghan M, ...
  • Fazaeli Y, Jalilian AR, Kamali-Dehghan M, Bolourinovin F, Moradkhani S, ...
  • Fazaeli Y, Jalilian AR, Amini MM, Aboudzadeh M, Feizi S, ...
  • Alirezapour B, Jalilian AR, Rasaee MJ, Rajabifar S, Yavari K, ...
  • Alirezapour B, Rasaee MJ, Jalilian AR, Rajabifar S, Mohammadnejad J, ...
  • https://www-nds.iaea.org/radionuclides/nip64cu0.html, Last updated: September 2008. ...
  • Cai Z, Anderson CJ. Chelators for copper radionuclides in positron ...
  • Cooper MS, Ma MT, Sunassee K, Shaw KP, Williams JD, ...
  • Wei L, Ye Y, Wadas TJ, Lewis JS, Welch MJ, ...
  • Fournier P, Dumulon-Perreault V, Ait-Mohand S, Langlois R, Bénard F, ...
  • Liu S, Li D, Huang CW, Yap LP, Park R, ...
  • Jalilian AR. An overview on Ga-68 radiopharmaceuticals for positron emission ...
  • Fani M, Maecke HR. Radiopharmaceutical development of radiolabelled peptides. Eur ...
  • Jalilian AR, Rowshanfarzad P, Kamrani YY, Shafaii K, Mirzaii M.. ...
  • Jalilian AR, Sabet M, Rowshanfarzad P, Kamali-Dehghan M, Akhlaghi M, ...
  • Handley MG, Medina RA, Nagel E, Blower PJ, Southworth R. ...
  • Maurer RI, Blower PJ, Dilworth JR, Reynolds CA, Zheng Y, ...
  • Torres JB, Andreozzi EM, Dunn JT, Siddique M, Szanda I, ...
  • Yip C, Blower PJ, Goh V, Landau DB, Cook GJ. ...
  • Medina RA, Mariotti E, Pavlovic D, Shaw KP, Eykyn TR, ...
  • Hueting R, Kersemans V, Cornelissen B, Tredwell M, Hussien K, ...
  • Fleming IN, Manavaki R, Blower PJ, West C, Williams KJ, ...
  • Takahashi N, Fujibayashi Y, Yonekura Y, Welch MJ, Waki A, ...
  • Lohith TG, Kudo T, Demura Y, Umeda Y, Kiyono Y, ...
  • Pfeifer A, Knigge U, Mortensen J, Oturai P, Berthelsen AK, ...
  • Wieser G, Mansi R, Grosu AL, Schultze-Seemann W, Dumont-Walter RA, ...
  • Philpott GW, Schwarz SW, Anderson CJ, Dehdashti F, Connett JM, ...
  • Persson M, Skovgaard D, Brandt-Larsen M, Christensen C, Madsen J, ...
  • Capasso E, Valentini MC, Mirzaei S, Knoll P, Meleddu C. ...
  • Capasso E, Durzu S, Piras S, Zandieh S, Knoll P, ...
  • Baharvand M, Manifar S, Akkafan R, Mortazavi H, Sabour S. ...
  • Peng F. Positron emission tomography for measurement of copper fluxes ...
  • https://clinicaltrials.gov/ct2/results term=64Cu&Search=Search ...
  • Persson M, Nedergaard MK, Brandt-Larsen M, Skovgaard D, Jørgensen JT, ...
  • Charoenphun P, Paul R, Weeks A, Berry D, Shaw K, ...
  • Hueting R. Radiocopper for the imaging of copper metabolism. J ...
  • Bandmann O, Weiss KH, Kaler SG. Wilson s disease and ...
  • Fodero-Tavoletti MT, Villemagne VL, Paterson BM, White AR, Li QX, ...
  • Pal A, Siotto M, Prasad R, Squitti R. Towards a ...
  • Vázquez MC, Martínez P, Alvarez AR, González M, Zanlungo S. ...
  • Smpokou P, Samanta M, Berry GT, Hecht L, Engle EC, ...
  • Sahlmann CO, Meller B, Bouter C, Ritter CO, Ströbel P, ...
  • Pyka T, Weirich G, Einspieler I, Maurer T, Theisen J, ...
  • McMillan DD, Maeda J, Bell JJ, Genet MD, Phoonswadi G, ...
  • Connett JM, Anderson CJ, Guo LW, Schwarz SW, Zinn KR, ...
  • Valentini G, Panichelli P, Villano C, Pigotti G, Martini D. ...
  • نمایش کامل مراجع