Adult-onset Still’s disease (AOSD)

Adult-onset Still’s disease (AOSD) is a rare clinical entity with unknown etiology, characterized by arthritis, fever, evanescent rash and other systemic presentations. This report described a 46 year-old female who presented with sore throat, fever, arthritis, evanescent rash, raised liver enzymes and hyperferritinemia. She was diagnosed to have AOSD based on Yamuguchi criteria after the exclusion of other potential diagnoses. The patient partially responded to combined NSAIDS and prednisolone. She was also prescribed methotrexate and her symptoms improved.