Toxicology Based on Traditional Iranian Medicine Sources and Evaluation of Zahr Mohra Mineral Stone or Serpentine as Pad-Zahr

Iranian traditional medicine is a precious legacy, compiled from the writings of the wise men of this region. In addition to the experience that has made a major contribution to the formation of this knowledge, the kind of specific philosophical attitude that is collectively called wisdom is involved.The compounds used in Iranian traditional medicine, including minerals, herbs, and animals, including food, medicine and poison, are in this branch of wisdom.Food, medicine, and poison have been defined as: food is a substance that becomes part of the body s tissue after it enters the body. Medication is a substance that causes changes in the body after it enters the body without affecting the body. Toxin is a substance that causes changes in the body that corrupt instinctive heat, spirits and forces. In other words, toxins can impair tissue structure and function. Due to the definition of the toxin and its mechanism of action, we have various debates in ancient toxicology.The following topics have been discussed in relation to the works of some scholars, such as Jaber ibn Hayyan, Ibn vahshie al-Nabati, and others:Definition of toxins, how to reach their place of action, mechanism of effect of toxins, inorganic, plant and animal toxins, combination toxins, benefits of some toxins, cold and hot toxins, use of toxins for different purposes, definition of antidote (Teryagh) and how it works, types of antidotes (Mufradat and Murakkabat), prevention of poisoning.Of all the debates about toxicology in the works of the wise, the most important is antidotes, which can be well achieved with new methods in examining their kinetics in new antidotes. Antidote is the Persian name of Teryaghat and is generally divided into two types, animal and mineral. In this study, a mineral antidote called Zahr mohra or Serpentine, which is a hydrogenated magnesium silicate [Mg6 (Si4O10) X (OH) 8 and is commercially known as green marble.Zahr mohra arises from metamorphism or due to hydrothermal activity at the final stage below 400 ° C from magnesium-rich rocks containing olivine, pyroxene or amphibole.Stone samples were collected from Iran, India and Pakistan. Crystallographic studies, XRD analysis, ICP/Mass and thermal gravimetry (TG) of the sample were performed and the crystalline structure and various elements present in the sample were identified. The crystalline structure of the sample is such that it can act as a heavy metal ion absorber. It is used in traditional Iranian medicine after a process called Kushtasazi as a singular drug and also in combination formulation as an antidote.