Comparison between the wound disinfection effects of alcohol-based and nanosilver-based solutions

Abstract:Introduction: Increase in the number of elderlies, medical advances and prolonged lives of chronic disease patients have introduced pressure, diabetic and vascular ulcers as one of the serious care issues in these patients. Ulcers are common, costly and life-threatening complications with adverse impacts on the physical, psychological and social life of the patients which can affect their quality of life infection due to incorrect disinfection of ulcers is one of the common problems which impose extra cost as well as prolonging the treated process.Aim: The aim of this study is to compare the impact of alcohol-based solution with silver-based ones in disinfection of ulcers.Method: This clinical trial was conducted on 60 patients with dregree-2 ulcer. The ulcer disinfection performance of alcohol-based solutions was compared with the silver-based ones, the ulcers of the patients were sampled and cultured before disinfection under similar condition. 38 samples were positive; half of them were disinfected with alcoholic solution while the other half was disinfected by silver-based solution. The samples were re-cultured. The data were analyzed by independent T test, Fischer test, Chi square, covariance analysis and pair T test using SPSS.Findings: After disinfecting with nanosilver solution, the ulcer infection was decreased by 75% while the other group showed a 38% decline. This means that ulcer disinfection with nanosilver solutions had significant difference with use of alcohol-based solution.Conclusion: The mean ulcer infection (before and after disinfection) was significantly different in alcohol-based and nanosilver-based solutions groups.

کلیدواژه ها:

alcohol-based solutions ، nanosilver-based solution ، ulcer disinfection