Newly in diagnosis of type 1 diabetes mellitus

Introduction: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.Materials & Methods: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.Results: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.Conclusion & discussion: Newly in diagnosis of type 1 diabetes mellitus As defined by the ADA, the diagnosis of diabetes is made when: fasting plasma glucose is 126 mg/dl ≤, 2-hour plasma glucose in oral glucose tolerance test 200 mg/dl ≤ , random glucose is 200 mg/dl ≤ in presence of classic symptoms of hyperglycemia, or HbA1c is 6.5% ≤. In pediatrics, HbA1c remains controversial. Differential diagnoses of diabetes are diagnostic challenges. For example, in transient benign hyperglycemia due to stress, plasma glucose may occasionally reach levels of 250-350 mg/dl. In this condition, insulin or c-peptide level will be elevated, but in new onset of type 1 diabetes will be inappropriately normal or mildly low. Also, measurement of diabetes auto antibodies with or without assessment of beta cell integrity by measuring FPIR can be decisive.

کلیدواژه ها:

type 1 diabetes ، diagnosis ، hyperglycemia