The antibacterial activity of an epoxy resin-based dental sealer containing bioactive glass, hydroxyapatite, and fluorohydroxyapatite nanoparticles against Enterococcus Faecalis and Streptococcus mitis

سال انتشار: 1399
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 470

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شناسه ملی سند علمی:

JR_NAMJ-7-1_002

تاریخ نمایه سازی: 24 دی 1398

چکیده مقاله:

Objective(s): The present study aimed to investigate the antibacterial properties of a conventional epoxy-based dental sealer modified with synthesized bioactive glass (BG), hydroxyapatite (HA), and fluorine-substituted hydroxyapatite (FHA) nano-fillers. Materials and Methods: The synthesized nano-fillers were incorporated into the conventional epoxy-based dental seaer at the concentration of 10%. The antimicrobial properties of the unmodified sealers (controls) and modified seaers with BG, HA, and FHA nanoparticles (NPs) were evaluated based on biofilm formation and using the direct contact test (DCT) of Enterococcus faecalis and Streptococcus mitis. Data analysis was performed using one-way analysis of variance (ANOVA) and Tukey’s post-hoc test at the significance level of 5%. Results: A significant reduction was observed in the biofilm formation and DCT of the microbial strains in the three modified groups compared to the unmodified conventional epoxy sealer (P<0.05). The addition of FHA NPs resulted in the most significant antibacterial effects against E. faecalis and S. mitis, as well as a statistically significant reduction compared to the unmodified and BG-modified groups (P≤0.001). Conclusion: According to the results of this preliminary study, nano-structured FHA, HA, and BG fillers incorporated into epoxy-based dental sealers could be potentially effective biomaterials for antibacterial approaches to root canal treatments.

نویسندگان

Bahaa Abdulrazzaq Jerri Al-Bakhsh

Department of Dental Biomaterials, School of Dentistry, International Campus, Tehran University of Medical Sciences, Tehran, Iran|Department of Endodontic, Dental School of the University of Basra, Basra, Iraq

Farhad Shafiei

Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran|Department of Dental Biomaterials, School of Dentistry/Research Center for Science and Technology in Medicine, Tehran University of Medical

Maryam Pourhajibagher

Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran|Dental Implant Research Center, Dentistry Research Institute, Tehran|Department of Microbiology, School of Medicine, Tehran

Kiana Shekofteh

Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran|Department of Dental Biomaterials, School of Dentistry/Research Center for Science and Technology in Medicine, Tehran University of Medical

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  • Lin LM, Skribner JE, Gaengler P. Factors associated with endodontic ...
  • Zhang H, Shen Y, Ruse ND, Haapasalo M. Antibacterial activity ...
  • Sundqvist G. Associations between microbial species in dental root canal ...
  • George M, Ivancakova R. Root canal microflora. Acta Medica (Hradec ...
  • AlShwaimi E, Bogari D, Ajaj R, Al-Shahrani S, Almas K, ...
  • Stuart CH, Schwartz SA, Beeson TJ, Owatz CB. Enterococcus faecalis: ...
  • Gjorgievska E, Apostolska S, Dimkov A, Nicholson JW, Kaftandzieva A. ...
  • Junior NBD, Collares FM, Genari B, de Souza Balbinot G, ...
  • Kangarlou A, Neshandar R, Matini N, Dianat O. Antibacterial efficacy ...
  • Baer J, Maki JS. In vitro evaluation of the antimicrobial ...
  • Collares FM, Leitune VCB, Portella FF, Santos PD, Balbinot GdS, ...
  • Barros J, Silva M, Rodrigues M, Alves F, Lopes M, ...
  • Samiei M, Farjami A, Dizaj SM, Lotfipour F. Nanoparticles for ...
  • Shrestha A, Kishen A. Antibacterial nanoparticles in endodontics: a review. ...
  • Tarle Z. Bioaktivni dentalni kompozitni materijali. Rad Hrvatske akademije znanosti ...
  • Kishen A. NANOTECHNOLOGY IN ENDODONTICS: Springer; 2016. ...
  • S. V. Dorozhkin ME. Biological and medical significance of calcium ...
  • Meskinfam M SM, Jazdarreh H, Zare K. Biocompatibility evaluation of ...
  • MM T-o, Gopalakrishnan V, Samsuddin A, Al Salihi K, Shamsuria ...
  • Makvandi P, Esposito Corcione C, Paladini F, Gallo AL, Montagna ...
  • Wei M EJ, Bostrom T, Grøndahl L. Synthesis and characterization ...
  • T A. The effect of fluoride on apatite structure and ...
  • Wiegand A, Buchalla W, Attin T. Review on fluoride-releasing restorative ...
  • Alhilou A, Do T, Mizban L, Clarkson BH, Wood DJ, ...
  • Hamilton I. Biochemical effects of fluoride on oral bacteria. J ...
  • Shafiei F, Behroozibakhsh M, Moztarzadeh F, Haghbin-Nazarpak M, Tahriri M. ...
  • Miles AA, Misra S, Irwin J. The estimation of the ...
  • Gilbert GH, Tilashalski KR, Litaker MS, McNeal SF, Boykin MJ, ...
  • Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K. ...
  • Al-Shwaimi E. Evaluation Of Antimicrobial Effect Of Root Canal Sealers. ...
  • Anumula L, Kumar S, Kumar VS, Sekhar C, Krishna M, ...
  • Wang L, Xie X, Li C, Liu H, Zhang K, ...
  • Editorial Board of the Journal of Endodontics. Wanted: a base ...
  • Hu S, Chang J, Liu M, Ning C. Study on ...
  • Munukka E, Leppäranta O, Korkeamäki M, Vaahtio M, Peltola T, ...
  • Korkut E, Torlak E, Altunsoy M. Antimicrobial and mechanical properties ...
  • Ragab H, Ibrahim F, Abdallah F, Al-Ghamdi AA, El-Tantawy F, ...
  • Chaughule RS. Dental Applications of Nanotechnology: Springer; 2018. ...
  • Song W, Ge S. Application of Antimicrobial Nanoparticles in Dentistry. ...
  • Sobierajska P, Dorotkiewicz-Jach A, Zawisza K, Okal J, Olszak T, ...
  • Wang L, Hu C, Shao L. The antimicrobial activity of ...
  • Wang L, He S, Wu X, Liang S, Mu Z, ...
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