Subconjunctival Myolipoma Confirmed with Immunohistochemical Analysis

Purpose: To describe clinicopathological features of subconjunctival myolipoma Methods: A 17-year-old female presented with a white-pink mass in the left upper bulbar conjunctiva. The lesion extended and finished in the forniceal conjunctiva. The patient revealed normal complete ocular examinations and underwent complete surgical excision of the mass due to cosmetic concerns. The tumor was examined with light– microscopy, following Hematoxylin and Eosin (H&E), Masson-trichrome, and Immunohistochemical (IHC) staining using the following antibodies: HMB45, actin, desmin, Estrogen Receptor (ER), S 100 protein as well as Smooth Muscle Actin (SMA).Results: A definite diagnosis of subconjunctival myolipoma was obtained following a detailed pathological assessment. Six months postoperatively, no tumor recurrence was noted, and ocular examinations were within normal limits. Conclusion: Myolipoma of the soft tissue is an exceedingly rare tumor with less than 50 reported cases in thecurrent literature and has female preponderance, and is commonly reported in the abdominal cavity and retroperitoneum. However, to date, only two cases of orbital myolipoma have been reported in the literature. The current report is the first case of subconjunctival myolipoma.