Effects of subthreshold diode micropulse laser photocoagulation on treating patients with refractory diabetic macular edema
محل انتشار: بیست و نهمین کنگره سالیانه انجمن چشم پزشکی ایران
سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 460
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شناسه ملی سند علمی:
ACSOMED29_034
تاریخ نمایه سازی: 30 آذر 1398
چکیده مقاله:
Purpose: To evaluate the effects of subthreshold diode micropulse laser photocoagulation on treating patients with refractory diabetic macularedema (DME) Methods: This randomized clinical trial recruited patients with DME in both eyes that were resistant to treatment with intravitreal bevacizumab(IVB). The eyes were randomly divided into two groups who received laser therapy and IVB, or IVB alone. Subthreshold diode micropulse laserphotocoagulation and IVB injection were administered in one eye, and an IVB injection was administered in the second eye. IVB injections wererepeated in both eyes within one month and two months after the first injection. Best corrected visual acuity (BCVA) logarithm of the minimumangle of resolution (logMAR) and central macular thickness (CMT) were measured before, within a month, and three months after start ofintervention. Results: In this study, 42 eyes of 21 patients were evaluated. The mean age of patients was 60.86±8.57 years. Ten patients (47.6%) were male.Within-group analysis showed a significant decreased in BCVA logMAR in the laser IVB group reflecting improvement in visual acuity (VA)(P<0.001); it increased in the control group during study reflecting more vision loss (P¼0.01). In the laser IVB group, a significant decreasein mean±standard deviation (SD) CMT at 3 months compared to baseline was observed (baseline: 513±126.29 vs. three months:408.1±95.28;P<0.001). The mean±SD CMT was significantly lower in the laser IVB group of eyes than in the control group three monthsafter intervention (P¼0.02). Conclusion: Using subthreshold diode micropulse laser photocoagulation in combination with IVB can significantly reduce CMT and improveBCVA in patients with refractory DME
نویسندگان
AR Dehghani
Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan IRAN
MR Akhlaghi
Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan IRAN
R pourmohamadi
Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan IRAN
Leila Asadpour,
Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan IRAN
m Pourazizi
Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan IRAN