Collimator Optimization Study of the High-Resolution SPECT Camera The GATE Monte Carlo Simulation

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 443

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شناسه ملی سند علمی:

RINMMICMED22_070

تاریخ نمایه سازی: 30 آذر 1398

چکیده مقاله:

Abstract: Molecular imaging is an essential tool for biomedical investigations using a small animal in various human disease models. This application usually requires imaging modalities with ultra-high spatial resolution and detection efficiency due to the animal size. Collimators play an important role in the nuclear medicine imaging and generally characterized by their image quality, sensitivity, and resolution. The most important factor for designing an optimized parallel-hole collimator is the collimator geometry. In this paper, the geometry of a preclinical SPECT (HiReSPECT) equipped with a pixelated CsI (Na) crystal (1×1×5 mm3 pixel size), lead hexagonal-hole collimator, and two flat panels H8500 PSPMTs is accurately described in the GATE code. After validation, we surveyed the effect of collimator hole shape on the performance of dual head camera by using the 99mTc source to find the optimal design. For this purpose, we designed two parallel-hole collimators with square and round-hole shapes. The results showed that the sensitivities of the hexagonal, square and round-hole collimators were 1.38, 1.23 and1.12 cps/μCi on the collimator surface respectively. The spatial resolution of the hexagonal hole was 7.78 and 11.88 % better than the square and round-hole collimators. An appropriate design of the collimator is very important in the gamma camera system, because it can significantly affect the performance of the imaging system. The hexagonal-hole collimators are generally desired over the square and round-hole collimators for most all medical imaging applications due to the optimum sensitivity and spatial resolution offered by such a close-packed arrangement of apertures.

نویسندگان

Zeinab Telikani

Department of Physics, Faculty of Science, University of Guilan, Rasht, Iran

Alireza Sadremomtaz

Department of Physics, Faculty of Science, University of Guilan, Rasht, Iran