Novel carrier for delivery of drug and simultaneous fluorescence imaging

Drug delivery systems are one of the most promising applications for human health care and represent an ever-evolving field for biomedical materials science [1]. In the area of drug delivery, looking for appropriate non-toxic carriers which is efficient for drugs delivery to the body is a crucial challenge [2].NMOFs possess some unique properties that enable them to perform as promising nanoplatforms for drug delivery and bioimaging. Firstly, NMOFs are compositionally and structurally diverse, allowing the facile synthesis of NMOFs with different compositions, shapes, sizes, and chemical properties. Secondly, NMOFs are biodegradable due to the presence of relatively labile metal ligand bonds; this feature makes it possible to rapidly degrade the composite material and release the loaded drug or probe [3].In summary, our experimental procedure involves the following steps: the hydrothermal method used to the synthesis of NMOF and the solvothermal method employed for the synthesis of N-CNDs. Then, hybrid nanocomposite (NMOF@N-CNDs) produced by the incorporation of the N-CNDs into NMOF. Afterwards, drug loaded into nanocomposite. So, this drug delivery vehicle can employ for simultaneous drug release and cell fluorescence imaging. Fluorescence imaging showed in Figure 1.