Comparison Level of Vitamin D in Follicular Fluid and Serum of Patients Candidate for Microinjection

Backgrounds: Vitamin D receptors in reproductive system of women including follicular fluid, endometrium, ovary, placenta, and serum plays a central role in fertility and improves fertilization. The purpose of this study was to compare the level of vitamin D in the follicular fluid and serum of candidates for microinjection.Material and method : The present study is a descriptive-analytic study. The study population is female infertility who referred to Motazedi Infertility Center for treatment through microinjection. A blood sample (5 ml) per day was collected from the premature vein in a fast-moving ovary from each patient and sent to the laboratory to determine vitamin D levels. The next level of blood vitamin D laboratory was recorded in the blood and follicular fluid in the questionnaires. Finally, the information obtained by the statistical expert was entered into the statistical software SPPS version 20 and analyzed statistically.Result: The mean age of 41 patients was 32 ± 6.02 years and the mean duration of infertility was 4.94 ± 2.63 years . The mean vitamin D level in the follicular fluid was 19.46 ± 11.55 ng / ml and the blood serum was 18.44 ± 10.36 ng / ml.The average number of Mature oocytes in the whole population was 6.30 ± 4.67 and the mean number of immature and decadent oocytes was 1.36 ± 1.24 in all patients. The mean number of embryos in the total number of patients was 4.11 ± 3.73 , There was no statistically significant difference between mean number of embryos at different levels of serum vitamin D (P=0.212) and follicular fluid (P= 0.429).The results showed that the mean thickness of the endometrium in the total population was 8.25 ± 1.72 mm. There was no statistically significant difference between the mean endometrial thickness at different levels of follicular fluid (P = 0.899) and female blood serum (P = 0.977).Conclusion: The results showed that there is no statistically significant difference between vitamin D levels, in follicular fluid and serum of patients with microinjection candidate.