General Health in Women with Polycystic Ovary Syndrome: Effect of Salvia Officinalis

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 281

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شناسه ملی سند علمی:

RROYAN20_400

تاریخ نمایه سازی: 29 مهر 1398

چکیده مقاله:

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age that has many psychological complications such as anxiety, depres-sion and mood disorders. Salvia officinalis (S. officinalis) is one the most famous herbal drugs that have potential effects on the central nervous system, cognitive performance, and mood. This study was designed to determine the effects of oral S. officinalis extract on mental health parameters in women with PCOS.Material and Methods: In the current randomized, Triple-blind, placebo-controlled trial, 60 PCOS patients were rand-omized to take either 330mg oral S. officinalis extract (n=30) or placebo (n=30) for 8 weeks. We used General health question-naire version 28 (GHQ -28) for assessment of mental health once before and once immediately after the intervention. All statistical analyses performed by using the SPSS software.Results: After 8 weeks oral S. officinalis extract intake resulted in a significant improvement in general health questionnaire total scores (P = 0.001), mental health status and increase in the number of people with a normal general health score (score below 24) (P = 0.031) ). In addition, the scores of GHQ-28 sub-scales in physical health (P = 0.001), anxiety (P = 0.001) and depression (P = 0.027) have been improved, but the scores of social performance did not change significantly (P= 0.495).Conclusion: Our study demonstrated that oral S. officinalis ex-tract use for 8 weeks among patients with PCOS had favorable effects on mental health status.

نویسندگان

L Amini

Department of Reproductive Health, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran