Diagnostic Chlamydia Trachomatis by PCR in Women with Frequent Abortions in Chalus (North of Iran)

Background: Chlamydia trachomatis (C. trachomatis) is a sex-ually transmitted disease, considered as one of the most com-mon causes of bacterial infections. This study aimed at scruti-nizing the Chlamydia trachomatis screening tests using vaginal samples. The relationship between Chlamydia trachomatis in-fection and abortion was also sought.Materials and Methods: In this case-control study which was conducted in Gynecology Clinic of Razi Hospital of Chalus, Iran from August 2017 to January 2018, a total of 50 vaginal swabs were collected. Detection of C. trachomatis DNA was performed from vaginal swabs by amplification of MOMP gene. Independent T-test and Chi-square were used for com-parison of quantitative and qualitative variables, respectively. P<0.05 was considered significant.Results: Examining the endocervical swabs of women revealed that the prevalence of C. trachomatis was obtained 5(10%). The prevalence of Chlamydia trachomatis infection in woman with abortion and in women with over 3 pregnancies was 10%. There were significant differences between chlamydia infection and du-ration of sexual activity. No significant difference was discovered between the presence of this infection and vaginal abnormalities. Conclusion: Those women with history of spontaneous abor-tion should be examined for presence of Chlamydia trachoma-tis infection and, necessary measures should be taken to avoid further miscarriages.

کلیدواژه ها:

Diagnostic ، Chlamydia Trachomatis ، PCR ، Frequent Abortions