Evidence Based Management of Recurrent Pregnancy Loss

Recurrent pregnancy loss (RPL), either early or late in the ges-tational period is a serious problem and has both psychological and social impacts on the women who suffer from it. In some cases, it may lead to divorce or other social problems. Recur-rent Pregnancy Loss (RPL), defined as two or more consecutive pregnancy losses, affecting 1–5 % of reproductive-age woman. There is a strong belief that RPL is a multifactorial condition that many factors affect such as chromosomal abnormalities, uterine anatomic malformation, endocrine dysfunction, throm-bophilia, immunologic factors, infections, and environmental factors. However, the etiology of RPL remains unknown in ~50 % of cases.This review presentation highlights the current understanding of the various etiologies implicated in RPL, including factors known to be causative, as well as those implicated as possible causative agents. The appropriate diagnostic evaluation, thera-py, and prognosis are also addressed.

کلیدواژه ها:

Recurrent Pregnancy Loss ، Spontaneous Abortion ، Habitual Abortion