Electroluminescence Cell Imaging Using A Novel Synthesized Cadmium Sulfide Quantum Dot

Background: Cadmium sulfide is one of the most widely used materials, due to its widespread use in optical instruments, solar cells, optical sensors, and bio-sensors.Materials and Methods: In this study, Cadmium Sulfide Quantum Dots (CdSQD) were successfully synthesized using an easy hydrothermal method with an average size of 6 nm. The synthesized CdSQD were characterized by Fourier trans-form infrared spectroscopy (FTIR), x-ray diffraction (XRD), Energy-dispersive X-ray spectroscopy (EDX), Scanning elec-tron microscopy (SEM) and Transmission electron microscopy (TEM). The optical properties of the CdSQD nanocomposites were measured in addition to its applications in cell imaging and photoluminescence. Fluorescent synthesized CdS in aque-ous solutions of MEMα medium has been optimized (1µg/ml) and The fluorescent properties of CdS used to monitor its up-take in HEK-293 cells. In this regard, cells were incubated with 1 μg/mL CdS for 3 h and then washed to remove any unbound Cds. It was observed the fluorescence pattern in most of HEK-293 cells when examined under fluorescence microscopy.Results: It has been demonstrated that such CdS nanoparticles can be used to image cell cultures and study the cell structure Conclusion: Synthesized quantum dot particles due to their small size, have high cell penetration, and this property can be used for pharmaceutical studies in medical science that avoids the side effects of some drugs, such as anticancer drugs. Be-cause these drugs should not be used at high doses to reduce damages so to the healthy cells of the body.

کلیدواژه ها:

Cadmium Sulfide Quantum Dot ، Hydrothermal Syn-thesis ، Photoluminescence ، Electroluminescence ، HEK-293 Cells