Study of Different Tissue Density Effects on the Dose Distribution of a 103Pd Brachytherapy Source Model MED3633
محل انتشار: مجله فیزیک پزشکی ایران، دوره: 7، شماره: 3
سال انتشار: 1389
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 247
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شناسه ملی سند علمی:
JR_IJMP-7-3_008
تاریخ نمایه سازی: 20 مهر 1398
چکیده مقاله:
Introduction: Clinical application of encapsulated radioactive brachytherapy sources has a major role in cancer treatment. In the present research, the effects of different tissue densities on the dose distribution of a 103Pd brachytherapy source in a spherical phantom of 50 cm radius have been studied. Material and Methods: As is well known, absorbed dose in tissue depends to its density, but this difference is not clear in measurements. Therefore, we applied the MCNP code to evaluate the effect of density on the dose distribution. 103Pd brachytherapy sources are used to treat prostate, breast and other cancers. Results: Absorbed dose has been calculated and presented around a source placed in the center of the phantom for different tissue densities. Also, we derived anisotropy and radial dose functions and compared our Monte Carlo results with experimental results of Rivard and Li et al. for F(1, θ) and g(r) in 1.040 g/cm3 tissue. Conclusion: The results of this study show that relative dose variations around the source center are very considerable at different densities, because of the presence of a photoabsorber (Au-Cu alloy) in the source core. Dose variation exceeds 80% at the point (Z = 2.4 mm, Y = 0 mm). Computed values of anisotropy and radial dose functions are in good agreement with the experimental results of Rivard and Li et al.
کلیدواژه ها:
نویسندگان
Ali Asghar Mowlavi
Associate Professor, Physics Dept., Faculty of Sciences, Sabzevar Tarbiat Moallem University, Sabzevar, Iran
Majed Yazdani
M.Sc of Physics, Physics Dept., Faculty of Sciences, Sabzevar Tarbiat Moallem University, Sabzevar, Iran