Evaluating The Relationship Between The Severity Of Psoriasis And The Prevalence Of Depression In Patients With Psoriasis Compared With Healthy Subjects Referred To Dermatology Clinics Of Gorgan In 2016-17

Introduction: Psoriasis is a systemic inflammatory disease and the most common recurrent chronic skindisease which affects almost 2% of the population and may occur at any age. This chronic disease causeschanges in the appearance that impairs the patients’ mental image of themselves and causes rejectionfrom society, isolation, personality disorders, depression, low self-esteem and weakened position of theperson in the family. Due to the lack of permanent recovery of patients with medications, psychiatricinterventions lead to improvements in the quality of life in these patients. An accurate assessment of therelationship between disease severity and psychopathology of it hasn’t been done in our society, so wedecided to assess the relationship between disease severity and depression rate in patients with psoriasisreferred to dermatology clinics is Gorgan in 2016-17 compared to healthy subjects.Method : In this case-control study, 68 patients with psoriasis referred to dermatology clinics in Gorganin 1395 and 68 normal controls were examined for depression using standard Beck (Beck II ) test.Severity of the disease was calculated based on Psoriasis Area Severity Index Score (PASI Score). Thedata gathered was analyzed using statistical tests with confidence level of 0.95, and statistical power of0.9 with SPSS software (version 18).Findings: This study evaluated 70 patients with psoriasis referred to dermatology clinics in Gorgan in2016-17 and 70 healthy subjects as controls. In each group 22 subjects were male (31.4%) and 48 subjectswere female (68.6%). Average disease severity was 35/17 ± 27 percent. With the increasing severity ofpsoriasis, the rate of depression is higher among patients. (P=0.0001) The rate of mild, moderate andsevere depression in the case group was higher than the control group. This difference is statisticallysignificant (p=0.0001)Conclusion: Depression symptoms are remarkably observed in psoriasis patients and the rate of thesesymptoms compared to healthy individuals is greater and these symptoms have a strong significantcorrelation with the severity of psoriasis.

کلیدواژه ها:

Depression ، psoriasis ، Beck II