Association of coronary artery disease with psoriasis in a group of patients in queen alia heart institute (qahi) in jordan

Objective: The aim of our study is to demonstrate the association between psoriasis and CAD in a group ofpatients at QUEEN ALIA HEART INSTITUTE (QAHI)..Methods: This retrospective study was conducted at QUEEN ALIA HEART INSTITUTE from April 2012 toAugust 2016. 167 psoriatic patients (with moderate to severe psoriasis) and 197 non-psoriatic patients (controlgroup) were matched by sex, age and risk factors of CAD. All patients underwent coronary angiography, andthe incidence of coronary artery disease was compared between the two groups.Results: After analysis, the p-value of CAD risk factors in both groups (psoriasis and controls) were: age (41.3year, 35.4 ,0.04) , male (67% , 64% ,0.06), smoking (60.5% , 56% , 0.4) , HTN (40.5 % , 43% , 0.29 ) ,DM(37.5% ,36.3% ,0.3), hyperlipidemia (20.3% , 17.8% , 0.41), family history (36.1% ,34..4 ,0.05). After matchingfor all these risk factors, the rate of CAD in psoriasis patients was (8.2%) and (2.1%) in non-psoriatic patientswith p-value less than 0.001.Conclusion: Psoriasis (moderate and severe) is an independent risk factor for increasing the risk of coronaryartery disease in (sex, age, and other risk factor for CAD) matched patients.

کلیدواژه ها:

Coronary artery disease ، Psoriasis ، coronary angiography